Gadolinium-enhanced MRI in cerebral Whipple's disease

Neuroradiology. 1993;35(8):581-3. doi: 10.1007/BF00588397.


Confusion developed in a 44-year-old man, who had diarrhoea and weight loss for three months. Jejunal biopsy showed infiltration by PAS-positive macrophages, indicating Whipple's disease. Cranial MRI disclosed multiple lesions mainly in the white matter and grey-white matter junction better demonstrated after gadolinium injection.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Biopsy
  • Brain / pathology*
  • Brain Diseases / diagnosis*
  • Contrast Media
  • Gadolinium
  • Humans
  • Jejunum / pathology
  • Magnetic Resonance Imaging / methods*
  • Male
  • Whipple Disease / diagnosis*


  • Contrast Media
  • Gadolinium