Differential distributions of the NMDA receptor channel subunit mRNAs in the mouse retina

Brain Res. 1994 Jan 21;634(2):328-32. doi: 10.1016/0006-8993(94)91938-0.

Abstract

In the retina, the epsilon 2 and zeta 1 subunit mRNAs of the NMDA receptor channel were expressed from embryonic stages and found in ganglion cell layer and whole layer of inner nuclear layer at postnatal day 21 (P21). The epsilon 1 subunit mRNA appeared postnatally and was distributed in ganglion cell layer and an inner third of inner nuclear layer at P21. These findings suggest that molecular organization of the NMDA receptor channel may alter during the retinal development.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Animals, Newborn / growth & development
  • Animals, Newborn / metabolism
  • Embryo, Mammalian / metabolism
  • Embryonic and Fetal Development
  • In Situ Hybridization
  • Ion Channels / genetics*
  • Mice
  • Mice, Inbred C57BL
  • RNA, Messenger / metabolism*
  • Receptors, N-Methyl-D-Aspartate / genetics*
  • Retina / embryology
  • Retina / growth & development
  • Retina / metabolism*
  • Tissue Distribution

Substances

  • Ion Channels
  • RNA, Messenger
  • Receptors, N-Methyl-D-Aspartate