Abstract
The attack on viruses and virus-infected cells by the mammalian immune system has provided considerable selective pressure for viruses that have evolved vigorous countermeasures to pre-empt, neutralize or evade this host attack. These countermeasures are astonishingly diverse, and their study imparts fundamental information about immunology and the mechanisms enabling viruses to survive and cause disease.
MeSH terms
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Animals
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Complement Inactivator Proteins / metabolism*
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Cytokines / antagonists & inhibitors*
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Cytokines / metabolism
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Histocompatibility Antigens Class I / metabolism*
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Humans
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Interferons / antagonists & inhibitors*
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Virulence
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Virus Diseases / immunology
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Virus Diseases / microbiology*
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Viruses / metabolism
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Viruses / pathogenicity*
Substances
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Complement Inactivator Proteins
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Cytokines
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Histocompatibility Antigens Class I
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Interferons