Cortical columns as devices for maximizing neuronal diversity

Trends Neurosci. 1994 Mar;17(3):101-4. doi: 10.1016/0166-2236(94)90113-9.


Columns are a fundamental feature of cerebral cortex organization, yet the function served by this architecture remains elusive. Here it is proposed that the columnar organization of the cortex serves to maximize diversity of neuronal connections in supragranular cortical layers.

Publication types

  • Review

MeSH terms

  • Animals
  • Cerebral Cortex / anatomy & histology
  • Cerebral Cortex / cytology
  • Cerebral Cortex / physiology*
  • Humans
  • Neurons / physiology*
  • Neurons / ultrastructure