Abstract
Transverse grooves of the nails, designated as Beau's lines, were observed in a patient with malignant lymphoma given chemotherapy. Beau's lines disappeared in the treatment-free intervals. This observation supports the concept that these lines are the result of the suppressed growth of the nail matrix caused by antimitotic drugs.
MeSH terms
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Aged
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Bleomycin / adverse effects
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Cisplatin / adverse effects
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Cyclophosphamide / adverse effects
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Dexamethasone / adverse effects
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Doxorubicin / adverse effects
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Etoposide / adverse effects
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Head and Neck Neoplasms / complications
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Head and Neck Neoplasms / drug therapy
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Humans
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Ifosfamide / adverse effects
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Lymphoma, Non-Hodgkin / complications
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Lymphoma, Non-Hodgkin / drug therapy
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Male
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Nail Diseases / chemically induced*
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Nail Diseases / pathology
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Nails / drug effects
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Nails / pathology
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Prednisone / adverse effects
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Vincristine / adverse effects
Substances
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Bleomycin
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Vincristine
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Etoposide
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Dexamethasone
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Doxorubicin
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Cyclophosphamide
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Cisplatin
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Ifosfamide
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Prednisone
Supplementary concepts
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DICE protocol
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VACOP-B protocol