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Review
. May-Jun 1994;28(3):209-19.

Nitric Oxide--From Mediator to Medicines

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Free PMC article
Review

Nitric Oxide--From Mediator to Medicines

P Vallance et al. J R Coll Physicians Lond. .
Free PMC article

Abstract

Nitric oxide is involved in a wide range of physiological processes in humans and in animals. It controls vascular tone, acts as a neurotransmitter and neuromodulator in the central and peripheral nervous systems and influences the activity of the immune system. Substances that selectively enhance or inhibit its synthesis or removal and modify its effects, are likely to yield interesting therapeutic agents.

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