The effect of smoking on sister chromatid exchange rate of newborn infants born to smoking mothers

Mutat Res. 1995 Feb;341(4):249-53. doi: 10.1016/0165-1218(95)90096-9.


Sister chromatid exchange (SCE) frequencies in lymphocytes of 21 smoking mothers and their 21 newborns were compared to those that of 10-infants whose mothers had never smoked and to those of 8 infants whose mothers were passive smokers and reported high exposure to tobacco smoke by living or working with smokers. Mothers in the first group also smoked throughout their pregnancy. Results confirm our earlier study on smoking effects reported for adults. Additionally, we saw that neonates have consistently lower SCE frequencies than adults.

MeSH terms

  • Adolescent
  • Adult
  • DNA Damage
  • Female
  • Humans
  • Infant, Newborn
  • Lymphocytes / pathology
  • Male
  • Pregnancy
  • Sister Chromatid Exchange*
  • Smoking / adverse effects*
  • Teratogens / toxicity*


  • Teratogens