[Lung fibrosis after bleomycin therapy]

Pneumonol Alergol Pol. 1994;62(9-10):520-5.
[Article in Polish]

Abstract

A case of lung fibrosis is presented in a 44 year old male in whom interstitial pulmonary changes were observed in the course of bleomycin therapy of malignant granulomatosis. Following introduction of corticosteroids a radiological, clinical and functional improvement was observed. The functional changes were analyzed during the 7 month period of treatment. This case suggests that post bleomycin induced injury can be reversed with appropriate high doses of corticosteroids.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Bleomycin / administration & dosage
  • Bleomycin / adverse effects*
  • Cisplatin / administration & dosage
  • Hodgkin Disease / drug therapy
  • Humans
  • Lung Neoplasms / drug therapy
  • Male
  • Mechlorethamine / administration & dosage
  • Prednisone / administration & dosage
  • Procarbazine / administration & dosage
  • Pulmonary Fibrosis / chemically induced*
  • Vincristine / administration & dosage
  • Vindesine / administration & dosage

Substances

  • Bleomycin
  • Procarbazine
  • Mechlorethamine
  • Vincristine
  • Cisplatin
  • Vindesine
  • Prednisone

Supplementary concepts

  • CVB protocol
  • MOPP protocol