Intermediate filaments: new proteins, some answers, more questions

Curr Opin Cell Biol. 1995 Feb;7(1):46-54. doi: 10.1016/0955-0674(95)80044-1.


The past year has seen significant progress in the characterization of intermediate filament proteins. New proteins have been identified and physiologically significant differences between known proteins have been revealed. Changes in intermediate filament organization have been linked to changes in cell behavior, and mutational analyses are beginning to reveal the connection between intermediate filament expression, network formation, cellular behavior and disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Animals
  • Biomarkers, Tumor / chemistry
  • Desmin / physiology
  • Intermediate Filament Proteins / physiology*
  • Keratins / physiology
  • Neurofilament Proteins / physiology
  • Vimentin / physiology


  • Biomarkers, Tumor
  • Desmin
  • Intermediate Filament Proteins
  • Neurofilament Proteins
  • Vimentin
  • Keratins