Characterization of the recognition site and diagnostic potential of an enterovirus group-reactive monoclonal antibody

Clin Diagn Lab Immunol. 1995 May;2(3):385-6. doi: 10.1128/cdli.2.3.385-386.1995.

Abstract

The epitope for a monoclonal antibody reactive against different enteroviruses was characterized. The epitope could be located to residues 40 to 48 of VP1, and the most-essential residues for monoclonal antibody binding coincided with those conserved among the majority of known enteroviruses, indicating a high diagnostic potential.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amino Acid Sequence
  • Antibodies, Monoclonal / immunology*
  • Antibodies, Monoclonal / metabolism
  • Binding Sites / immunology
  • Enterovirus / immunology*
  • Enterovirus / isolation & purification
  • Enterovirus Infections / diagnosis*
  • Epitopes / immunology
  • Humans
  • Molecular Sequence Data
  • Peptides / immunology
  • Viral Proteins / immunology

Substances

  • Antibodies, Monoclonal
  • Epitopes
  • Peptides
  • Viral Proteins