Are you sure it's syphilis? A review of false positive serology

Int J STD AIDS. 1995 Jul-Aug;6(4):241-8. doi: 10.1177/095646249500600404.


This article on false positive serological reactions for syphilis reviews the rapid developments which have taken place in the serodiagnosis of syphilis in recent years since the advent of the AIDS epidemic. An overview of non-specific and specific treponemal serological tests in relation to acute and chronic biological false positive reactions is followed by closer consideration of syphilis serology in the context of HIV infection, pregnancy and other conditions which may produce false positive reactions.

Publication types

  • Review

MeSH terms

  • AIDS-Related Opportunistic Infections / blood
  • Acute Disease
  • Chronic Disease
  • Diagnosis, Differential
  • False Positive Reactions
  • Female
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / blood
  • Syphilis / diagnosis*
  • Syphilis Serodiagnosis / methods*