Disease due to Mycobacterium kansasii in the Czech Republic: 1984-89

Tuber Lung Dis. 1995 Jun;76(3):205-9. doi: 10.1016/s0962-8479(05)80006-1.


Setting: Endemic area of North Moravia, Czech Republic.

Objective: Evaluate the incidence of human disease due to Mycobacterium kansasii. The follow-up of some bacteriological and clinical features.

Design: A retrospective analysis of M. kansasii patients.

Results: M. kansasii was isolated from the sputum, tissue and other specimens obtained from 650 persons during the period 1984-89. In only 471 of them was this mycobacterium deemed to be the causative agent, predominantly of lung disease. The most typical radiographic finding in these patients was lung infiltration and/or thin-walled cavity.

Conclusion: As in previous years the highest incidence of disease remains in an endemic area of North Moravia. The effects of treatment in follow-up patients were influenced not only by the antituberculosis regimen but also by a high frequency of associated diseases. Sputum conversion within 30 days was not affected by the presence or absence of a cavity. Authors consider water to be the source of infection.

MeSH terms

  • Anti-Bacterial Agents
  • Antitubercular Agents / therapeutic use
  • Czech Republic / epidemiology
  • Drug Resistance, Microbial
  • Drug Therapy, Combination / therapeutic use
  • Female
  • Humans
  • Male
  • Middle Aged
  • Mycobacterium Infections, Nontuberculous / complications
  • Mycobacterium Infections, Nontuberculous / epidemiology*
  • Mycobacterium Infections, Nontuberculous / microbiology
  • Nontuberculous Mycobacteria / isolation & purification*
  • Retrospective Studies
  • Rifampin / therapeutic use
  • Tuberculosis, Pulmonary / complications


  • Anti-Bacterial Agents
  • Antitubercular Agents
  • Rifampin