Recognition system for dietary fatty acids in the rat small intestine

T Shintani; N Takahashi; T Fushiki; J Kotera; E Sugimoto

doi:10.1271/bbb.59.1428

Recognition system for dietary fatty acids in the rat small intestine

Biosci Biotechnol Biochem. 1995 Aug;59(8):1428-32. doi: 10.1271/bbb.59.1428.

Authors

T Shintani¹, N Takahashi, T Fushiki, J Kotera, E Sugimoto

Affiliation

¹ Department of Food Science and Technology, Faculty of Agriculture, Kyoto University, Japan.

PMID: 7549092
DOI: 10.1271/bbb.59.1428

Abstract

Linoleic acid and oleic acid markedly increased the influx of 45Ca into isolated intestinal epithelial cells, and this increase reflected a rise in the intracellular calcium level. Methyl linoleate had no effect, while glutamic acid and somatostatin both inhibited the linoleic acid-induced influx of 45Ca. In addition, methyl linoleate had no effect, while glutamic acid inhibited linoleic acid-induced hormone-responsive pancreatic exocrine secretion.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Aspartic Acid / pharmacology
Calcium / metabolism*
Cells, Cultured
Dietary Fats / pharmacology*
Gastrointestinal Hormones / metabolism
Glutamic Acid / pharmacology
Intestinal Mucosa / cytology
Intestine, Small / cytology
Intestine, Small / metabolism*
Linoleic Acid
Linoleic Acids / pharmacology
Oleic Acid
Oleic Acids / pharmacology
Pancreas / metabolism
Rats
Receptors, N-Methyl-D-Aspartate / metabolism

Substances

Dietary Fats
Gastrointestinal Hormones
Linoleic Acids
Oleic Acids
Receptors, N-Methyl-D-Aspartate
methyl linoleate
Oleic Acid
Aspartic Acid
Glutamic Acid
Linoleic Acid
Calcium