[Effect of Astragalus membranaceus on T-lymphocyte subsets in patients with viral myocarditis]

Zhongguo Zhong Xi Yi Jie He Za Zhi. 1995 Jun;15(6):328-30.
[Article in Chinese]


The efficacy of Astragalus membranaceus (AM) oral liquor combined with routine therapy and routine therapy alone on T-lymphocyte subsets of peripheral blood in viral myocarditis patients have been studied. The results showed that the T-lymphocyte subsets profile and OKT4/OKT8 ratio of peripheral blood were significantly lower in viral myocarditis patients than that in healthy control (P < 0.05, 0.01). Routine therapy combined with AM could significantly enhance OKT3, OKT4 and OKT4/OKT8 ratio in the above-mentioned patients (P < 0.05, 0.01). The possible pharmacodynamic mechanism of improved cell immunity in viral myocarditis patients by combining routine therapy with AM was discussed.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Astragalus propinquus
  • CD4-CD8 Ratio
  • Drugs, Chinese Herbal / administration & dosage*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Myocarditis / drug therapy*
  • Myocarditis / immunology
  • Myocarditis / virology
  • T-Lymphocyte Subsets / immunology*
  • Virus Diseases / drug therapy*
  • Virus Diseases / immunology


  • Drugs, Chinese Herbal