Amniotic membrane as a cover for microskin grafts

Br J Plast Surg. 1995 Oct;48(7):477-8. doi: 10.1016/0007-1226(95)90123-x.


Twenty two granulating wounds were grafted with microskin grafts of 1 mm size and amniotic membrane was used to cover these grafts. In 16 patients, epithelialisation was complete by 10 days and the grafts remained stable. Fifteen-fold expansion was achieved in all these cases. The remaining 6 patients needed split thickness skin grafts due to failure of the microskin grafts. Human amniotic membrane as a cover for microskin grafts helped early epithelialisation and rapid wound healing.

MeSH terms

  • Adolescent
  • Adult
  • Biological Dressings*
  • Burns / complications
  • Child
  • Child, Preschool
  • Female
  • Granulation Tissue / surgery*
  • Humans
  • Leg Ulcer / complications
  • Male
  • Middle Aged
  • Skin Transplantation / methods*
  • Wound Healing