Swarming and pathogenicity of Proteus mirabilis in the urinary tract

Trends Microbiol. 1995 Jul;3(7):280-4. doi: 10.1016/s0966-842x(00)88945-3.


Proteus mirabilis is best known for its pattern of swarming differentiation on agar plates, as well as for its association with the development of renal stones in patients with urinary tract infection. Urease and flagella appear to contribute most significantly to virulence, with fimbriae playing a more subtle role, whereas hemolysin does not appear to contribute significantly to pathogenesis.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Humans
  • Proteus Infections / microbiology*
  • Proteus mirabilis / genetics
  • Proteus mirabilis / growth & development
  • Proteus mirabilis / pathogenicity*
  • Urinary Tract Infections / microbiology*