Somite differentiation. Sonic signals somites

Curr Biol. 1995 Jun 1;5(6):612-4. doi: 10.1016/s0960-9822(95)00123-0.

Abstract

Sonic hedgehog, a secreted signalling molecule known to play a role in the patterning of the central nervous system and the limb in vertebrates, also controls differentiation of the somites.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Animals
  • Cell Differentiation
  • Chick Embryo
  • Embryonic Induction / physiology*
  • Embryonic and Fetal Development / physiology
  • Hedgehog Proteins
  • Homeodomain Proteins / physiology
  • Mesoderm / cytology
  • Mesoderm / physiology*
  • Mice
  • Morphogenesis / physiology*
  • Notochord / physiology
  • Notochord / transplantation
  • Proteins / physiology*
  • Trans-Activators*
  • Transcription Factors / physiology
  • Vertebrates / embryology*

Substances

  • Hedgehog Proteins
  • Homeodomain Proteins
  • Proteins
  • Trans-Activators
  • Transcription Factors