Hypoadrenocorticism in a family of leonbergers

J Am Anim Hosp Assoc. 1995 Jul-Aug;31(4):301-5. doi: 10.5326/15473317-31-4-301.

Abstract

Hypoadrenocorticism was diagnosed in four related leonbergers. Two of the four dogs also had low-resting serum thyroxine (T4) levels and signs consistent with hypothyroidism. The familial association of the affected dogs and the presence of coexisting thyroid dysfunction are similar to what is seen in human type II polyglandular autoimmune syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Adrenal Insufficiency / diagnosis
  • Adrenal Insufficiency / drug therapy
  • Adrenal Insufficiency / genetics
  • Adrenal Insufficiency / veterinary*
  • Animals
  • Dog Diseases / diagnosis*
  • Dog Diseases / drug therapy
  • Dog Diseases / genetics
  • Dogs
  • Drug Therapy, Combination
  • Female
  • Pedigree
  • Thyroxine / blood

Substances

  • Adrenal Cortex Hormones
  • Thyroxine