der(1;15)(q10;10): a nonrandom chromosomal abnormality of myeloid neoplasia

K F Wong; K J Hayes; A B Glassman

doi:10.1016/0165-4608(95)00041-m

der(1;15)(q10;10): a nonrandom chromosomal abnormality of myeloid neoplasia

Cancer Genet Cytogenet. 1995 Sep;83(2):144-7. doi: 10.1016/0165-4608(95)00041-m.

Authors

K F Wong¹, K J Hayes, A B Glassman

Affiliation

¹ Section of Cytogenetics, Anderson Cancer Center, Houston, Texas 77030, USA.

PMID: 7553585
DOI: 10.1016/0165-4608(95)00041-m

Abstract

The occurrence of an unusual karyotypic abnormality der(1;15)(q10;q10) is reported in three patients, one with acute megakaryoblastic leukemia and two with myelodysplastic syndrome. A literature review shows that this cytogenetic abnormality is a rare but nonrandom change in myeloid neoplasia/neoplasia.

Publication types

Case Reports
Research Support, Non-U.S. Gov't
Review

MeSH terms

Aged
Child, Preschool
Chromosomes, Human, Pair 1*
Chromosomes, Human, Pair 15*
Female
Humans
Karyotyping
Leukemia, Megakaryoblastic, Acute / genetics*
Male
Middle Aged
Myelodysplastic Syndromes / genetics*
Translocation, Genetic*