Somatic hypermutation: how many mechanisms diversify V region sequences?

Cell. 1995 Oct 6;83(1):9-12. doi: 10.1016/0092-8674(95)90227-9.
No abstract available

Publication types

  • Review

MeSH terms

  • Animals
  • Antibody Affinity
  • Antibody Diversity / physiology*
  • Antigen-Antibody Reactions
  • DNA Nucleotidyltransferases / physiology
  • DNA Repair
  • Gene Conversion
  • Gene Rearrangement, B-Lymphocyte / physiology*
  • Gene Rearrangement, T-Lymphocyte
  • Germinal Center / cytology
  • Immunoglobulin Variable Region / genetics*
  • Mice
  • Models, Genetic
  • Mutation*
  • Selection, Genetic
  • Species Specificity
  • Templates, Genetic
  • Transcription, Genetic
  • VDJ Recombinases
  • Vertebrates / immunology

Substances

  • Immunoglobulin Variable Region
  • DNA Nucleotidyltransferases
  • VDJ Recombinases