Cloning and Sequence of the Bordetella Bronchiseptica Adenylate Cyclase-Hemolysin-Encoding Gene: Comparison With the Bordetella Pertussis Gene

Gene. 1995 Aug 30;162(1):165-6. doi: 10.1016/0378-1119(95)00339-8.


The cyaA gene from Bordetella bronchiseptica (Bb), encoding the adenylate cyclase-hemolysin (AC-Hly), has been cloned and its complete nucleotide sequence has been determined. The deduced amino-acid sequence was compared to the AC-Hly from B. pertussis (Bp) and the main differences were found in the C-terminal repeat region of the molecule.

Publication types

  • Comparative Study

MeSH terms

  • Adenylate Cyclase Toxin
  • Adenylyl Cyclases / genetics*
  • Amino Acid Sequence
  • Bacterial Proteins / genetics*
  • Bordetella bronchiseptica / enzymology
  • Bordetella bronchiseptica / genetics*
  • Bordetella pertussis / genetics
  • Cloning, Molecular
  • Genes, Bacterial*
  • Hemolysin Proteins / genetics*
  • Molecular Sequence Data
  • Protein Precursors / genetics*
  • Sequence Analysis, DNA
  • Sequence Homology, Amino Acid
  • Species Specificity


  • Adenylate Cyclase Toxin
  • Bacterial Proteins
  • Hemolysin Proteins
  • Protein Precursors
  • Adenylyl Cyclases

Associated data

  • GENBANK/Z37112