Detection of deep myometrial invasion in endometrial carcinoma: comparison of transvaginal ultrasound, CT, and MRI

J Comput Assist Tomogr. 1995 Sep-Oct;19(5):766-72. doi: 10.1097/00004728-199509000-00013.

Abstract

Objective: The aim of this study was to compare the accuracy of transvaginal US (TVUS), CT, and MRI in detecting deep myometrial invasion in endometrial carcinoma.

Materials and methods: Twenty-six patients with endometrial carcinoma were evaluated with TVUS, CT, and MRI. The depth of myometrial invasion was estimated in each examination. The invasion depth was categorized into no/superficial and deep and was compared to surgical and pathologic findings.

Results: At pathologic examination, the depth of myometrial invasion was no/superficial in 16 patients and deep in 10. The accuracy/sensitivity/specificity of TVUS, CT, and MRI in detecting deep myometrial invasion were 69/50/81, 61/40/75, and 89%/90%/88%, respectively. The sensitivity and accuracy of MRI in detecting deep myometrial invasion were significantly higher than those of TVUS and CT (p = 0.049 for both sensitivity and accuracy).

Conclusion: We recommend MRI instead of CT or TVUS for the evaluation of the depth of myometrial invasion in endometrial carcinoma.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenocarcinoma / diagnostic imaging
  • Adenocarcinoma / pathology
  • Adult
  • Aged
  • Carcinoma / diagnosis*
  • Carcinoma / diagnostic imaging*
  • Carcinoma / pathology
  • Carcinoma, Adenosquamous / diagnostic imaging
  • Carcinoma, Adenosquamous / pathology
  • Contrast Media
  • Dilatation and Curettage
  • Endometrial Neoplasms / diagnostic imaging*
  • Endometrial Neoplasms / pathology*
  • Female
  • Humans
  • Hysterectomy
  • Lymph Node Excision
  • Magnetic Resonance Imaging*
  • Middle Aged
  • Myometrium / diagnostic imaging*
  • Myometrium / pathology*
  • Neoplasm Invasiveness
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed*
  • Ultrasonography
  • Uterine Neoplasms / diagnosis*
  • Uterine Neoplasms / diagnostic imaging*
  • Uterine Neoplasms / pathology

Substances

  • Contrast Media