The occurrence of breast carcinoma in regard to mammographic parenchyma samples applying the technique of Wolfe was analyzed. In the examined group of patients (n = 105) after clinical and mammographic examination mastectomy was performed with evacuation of axillary tissue. The malignancy was confirmed pathohistologically as well as the degree of spreading. The control group consisted of (n = 105) patients of the same age in whom at the time of examination and 6 months later malignancy was not confirmed. P-2 was more frequent in the group of the sick, while N-1 sample (X2 = 17.15, p < 0.01) was rarer. In patients older than 50 years of age Dy sample (x2 = 11.95, p < 0.01) was also more frequent. The difference can be explained by the fact that P-2 and Dy mammographic samples represent the picture of dysplastically changed breast tissue and depending on the presence of histologic elements of proliferation and cell atypias point to an increased risk of cancer. Consequently the samples are divided into "highly risky" (P-2 and Dy) and "of low risk" (N-1 and P-1). Women with mammographic parenchymal samples of a higher risk together with other risk factors should be frequently controlled.