Three cases of pulmonary aspergilloma in adult patients with cystic fibrosis

Thorax. 1995 Jul;50(7):805-6. doi: 10.1136/thx.50.7.805.


Pulmonary aspergillomas usually occur when Aspergillus fungi colonise lung tissue previously damaged by disease. Pulmonary aspergillomas in three adult patients with cystic fibrosis are reported--an association not previously described. At the time of diagnosis all three patients had previous long term colonisation with Aspergillus fumigatus and severe advanced destructive lung disease with lung function less than 25% of the predicted normal values. It is likely that, with increasing survival in cystic fibrosis, more adult patients will develop aspergillomas during the protracted phase of end stage lung disease that characterises the terminal years of this condition.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aspergillosis / complications*
  • Aspergillus fumigatus
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / diagnostic imaging
  • Cystic Fibrosis / microbiology
  • Fatal Outcome
  • Female
  • Humans
  • Lung Diseases, Fungal / complications*
  • Lung Diseases, Fungal / diagnostic imaging
  • Radiography