An outbreak of naphthalene di-isocyanate-induced asthma in a plastics factory

Arch Environ Health. Sep-Oct 1995;50(5):337-40. doi: 10.1080/00039896.1995.9935964.


Seven cases of possible naphthalene di-isocyanate-related occupational asthma occurred in 1987 and 1988. These cases were reported to the National Institute for Occupational Safety and Health by personnel at a Midwest factory that manufactured plastic wheels for fork-lift trucks. The reporting of cases prompted (a) an evaluation of the workplace, including a medical screening of workers, to detect additional cases; and (b) an industrial-hygiene survey to determine the level of exposure to isocyanates.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Asthma / chemically induced*
  • Asthma / diagnosis
  • Disease Notification
  • Disease Outbreaks*
  • Environmental Monitoring
  • Female
  • Humans
  • Isocyanates / adverse effects*
  • Mass Screening
  • Middle Aged
  • Occupational Diseases / chemically induced*
  • Occupational Diseases / diagnosis
  • Plastics
  • Spirometry


  • Isocyanates
  • Plastics
  • 1,5-naphthylene di-isocyanate