Antibacterial activity of flavanostilbenes against methicillin-resistant Staphylococcus aureus

M Sato; H Tsuchiya; T Miyazaki; M Ohyama; T Tanaka; M Iinuma

doi:10.1111/j.1472-765x.1995.tb01045.x

Antibacterial activity of flavanostilbenes against methicillin-resistant Staphylococcus aureus

Lett Appl Microbiol. 1995 Oct;21(4):219-22. doi: 10.1111/j.1472-765x.1995.tb01045.x.

Authors

M Sato¹, H Tsuchiya, T Miyazaki, M Ohyama, T Tanaka, M Iinuma

Affiliation

¹ Department of Oral Microbiology, Asahi University School of Dentistry, Gifu, Japan.

PMID: 7576511
DOI: 10.1111/j.1472-765x.1995.tb01045.x

Abstract

Three phytochemical compounds (alopecurone A-C), flavanostilbenes which are produced by condensation between a hydroxyflavanone and a hydroxystilbene, were isolated as major components from the root of Sophora alopecuroides. They uniformly inhibited the growth of 21 strains of methicillin-resistant Staphylococcus aureus with minimum inhibitory concentrations of 3.13-6.25 micrograms ml-1.

MeSH terms

Anti-Bacterial Agents / chemistry
Anti-Bacterial Agents / isolation & purification
Anti-Bacterial Agents / pharmacology*
Fabaceae / chemistry*
Methicillin Resistance*
Microbial Sensitivity Tests
Plant Extracts / chemistry
Plant Extracts / isolation & purification
Plant Extracts / pharmacology
Plants, Medicinal*
Staphylococcus aureus / drug effects*
Staphylococcus aureus / growth & development

Substances

Anti-Bacterial Agents
Plant Extracts