Yeast RNA polymerase III: transcription complexes and RNA synthesis

E P Geiduschek; C Bardeleben; C A Joazeiro; G A Kassavetis; S Whitehall

Yeast RNA polymerase III: transcription complexes and RNA synthesis

Braz J Med Biol Res. 1995 Feb;28(2):147-59.

Authors

E P Geiduschek¹, C Bardeleben, C A Joazeiro, G A Kassavetis, S Whitehall

Affiliation

¹ Department of Biology, University of California, San Diego, La Jolla 92093-0634, USA.

PMID: 7581036

Abstract

In this article we review and summarize salient features of the mechanism of transcription by eukaryotic RNA polymerase III, focusing a considerable part of the account on the work of our laboratory, dealing with Saccharomyces cerevisiae, but emphasizing properties that are common to all eukaryotic RNA polymerases. The following topics are briefly discussed: promoter structure; transcription factors; internal structure of transcription complexes and DNA-protein interactions; U6 genes; promoter opening and RNA chain elongation; hydrolytic RNA retraction.

Publication types

Review

MeSH terms

Animals
Promoter Regions, Genetic / genetics*
RNA Polymerase III / genetics*
RNA, Fungal / biosynthesis*
Ribonucleoprotein, U4-U6 Small Nuclear / genetics*
Saccharomyces cerevisiae / genetics*
Transcription Factors / physiology*

Substances

RNA, Fungal
Ribonucleoprotein, U4-U6 Small Nuclear
Transcription Factors
RNA Polymerase III