Hammerhead ribozyme structure: U-turn for RNA structural biology

Structure. 1995 Aug 15;3(8):747-50. doi: 10.1016/s0969-2126(01)00208-8.


Two crystal structures of the hammerhead ribozyme provide the first atomic-resolution views of an RNA active site, and suggest that the catalytic center may reside in a U-turn motif which was first seen in tRNA(Phe).

Publication types

  • Review

MeSH terms

  • Base Sequence
  • Binding Sites
  • Catalysis
  • Cations, Divalent
  • Models, Molecular
  • Molecular Sequence Data
  • Nucleic Acid Conformation*
  • RNA, Catalytic / chemistry*
  • RNA, Catalytic / metabolism
  • Ribose


  • Cations, Divalent
  • RNA, Catalytic
  • Ribose