Functions of fibroblast growth factors and their receptors

Curr Biol. 1995 May 1;5(5):500-7. doi: 10.1016/s0960-9822(95)00102-3.

Abstract

Fibroblast growth factors were first characterized twenty years ago as mitogens of cultured fibroblasts. Despite a wealth of data from experiments in vitro, insights have begun to emerge only recently on the normal function of these growth factors in mice and humans, as a result of studies of natural and experimental mutations in the factors and their receptors.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Fibroblast Growth Factors / chemistry
  • Fibroblast Growth Factors / physiology*
  • Humans
  • Ligands
  • Molecular Sequence Data
  • Mutation
  • Protein Conformation
  • Receptors, Fibroblast Growth Factor / chemistry
  • Receptors, Fibroblast Growth Factor / physiology*

Substances

  • Ligands
  • Receptors, Fibroblast Growth Factor
  • Fibroblast Growth Factors