Intracellular signalling. Switching off signals

J B Imboden; G A Koretsky

doi:10.1016/s0960-9822(95)00145-x

Intracellular signalling. Switching off signals

Curr Biol. 1995 Jul 1;5(7):727-9. doi: 10.1016/s0960-9822(95)00145-x.

Authors

J B Imboden¹, G A Koretsky

Affiliation

¹ Department of Medicine, Veterans Affairs Medical Center, San Francisco, California, USA.

PMID: 7583115
DOI: 10.1016/s0960-9822(95)00145-x

Abstract

In hematopoietic cells, the protein tyrosine phosphatase PTP1C appears to play a central role in the termination of signalling by receptors that activate protein tyrosine kinases.

Publication types

Review

MeSH terms

Animals
Enzyme Activation
Hematopoietic Stem Cells / enzymology
Hematopoietic Stem Cells / metabolism*
Intracellular Signaling Peptides and Proteins
Protein Tyrosine Phosphatase, Non-Receptor Type 11
Protein Tyrosine Phosphatase, Non-Receptor Type 6
Protein Tyrosine Phosphatases / metabolism*
Protein-Tyrosine Kinases / metabolism*
Signal Transduction*

Substances

Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Protein Tyrosine Phosphatase, Non-Receptor Type 11
Protein Tyrosine Phosphatase, Non-Receptor Type 6
Protein Tyrosine Phosphatases