Vitamin A Megatherapy for Retinal Abnormalities

Nat Med. 1995 Sep;1(9):884-5. doi: 10.1038/nm0995-884.

MeSH terms

  • Adult
  • Age of Onset
  • Bruch Membrane / metabolism
  • Chromosome Mapping
  • Chromosomes, Human, Pair 22
  • Extracellular Matrix / metabolism
  • Fundus Oculi*
  • Genes, Dominant
  • Humans
  • Macular Degeneration / drug therapy*
  • Macular Degeneration / epidemiology
  • Macular Degeneration / genetics
  • Models, Molecular
  • Point Mutation
  • Protein Conformation
  • Proteins / chemistry
  • Proteins / genetics*
  • Tissue Inhibitor of Metalloproteinase-3
  • Vitamin A / administration & dosage
  • Vitamin A / therapeutic use*

Substances

  • Proteins
  • Tissue Inhibitor of Metalloproteinase-3
  • Vitamin A