Parathyroid adenomas without sestamibi retention

Clin Nucl Med. 1995 Aug;20(8):699-702. doi: 10.1097/00003072-199508000-00008.


The authors describe two patients in whom parathyroid adenomas were successfully localized with a Tc-99m sestamibi/pertechnetate subtraction technique, but who did not exhibit differential sestamibi retention on delayed imaging. Although the frequency of this occurrence is unclear, it suggests that some parathyroid adenomas will be missed if reliance is placed on sestamibi retention alone without simultaneous thyroid imaging.

Publication types

  • Case Reports

MeSH terms

  • Adenoma / diagnostic imaging*
  • Adult
  • Female
  • Humans
  • Middle Aged
  • Parathyroid Neoplasms / diagnostic imaging*
  • Radionuclide Imaging
  • Sodium Pertechnetate Tc 99m*
  • Subtraction Technique
  • Technetium Tc 99m Sestamibi*


  • Technetium Tc 99m Sestamibi
  • Sodium Pertechnetate Tc 99m