Priorities in global measles control: report of an outbreak in N'Djamena, Chad

Epidemiol Infect. 1995 Oct;115(2):309-14. doi: 10.1017/s095026880005843x.

Abstract

In N'Djamena, capital of Chad, measles vaccination coverage of 12-23-month-old children fell from 61% in 1990 to 15% in 1993. A community survey of measles after an outbreak in 1993 showed that among children < 5 years of age, the mean monthly attack rate was 37 per 1,000 (95% CI, 32-43) and the mean case fatality rate was 7.4%. Measles incidence was highest (77/1,000/month) in children aged 9-11 months and fell among children > 3 years of age. Incidence rates were high (56/1,000/month) among 6-8-month-old children, but only 3 deaths occurred in this age group. Measles vaccine efficacy, estimated by comparing attack rates in unvaccinated and vaccinated children, was 71% (95% CI, 59-80%). Extrapolation of the results to the city population indicated that an estimated 19,000 cases and > 1,000 measles-associated deaths occurred in 1993. This preventable morbidity and mortality, in a city where coverage was formerly among the highest in Africa, shows the need for sustained global commitment to preventive health care.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Age Distribution
  • Chad / epidemiology
  • Child, Preschool
  • Disease Outbreaks*
  • Female
  • Humans
  • Incidence
  • Infant
  • Male
  • Measles / epidemiology*
  • Measles / prevention & control*
  • Measles Vaccine*
  • Population Surveillance
  • Risk Factors
  • Seasons
  • Urban Health
  • Vaccination / statistics & numerical data
  • Vaccination / trends

Substances

  • Measles Vaccine