Synovectomy or total replacement of the knee in hemophilia

J Bone Joint Surg Am. 1979 Jan;61(1):69-75.


Eighteen major operations on the knee joint were performed in sixteen patients with hemophilia, eight operations being synovectomy and ten being total knee replacement. Synovectomy was performed for recurrent bleeding associated with synovitis. The average age at operation for patients who underwent synovectomy was 16.4 years, and the average follow-up was thirty-one months. No patient had a recurrent hemorrhage following synovectomy. The patients who had total knee arthroplasty for disabling pain had an average age at surgery of 35.7 years and an average follow-up of twenty-three months. The pain was markedly reduced in all eight patients and all achieved full unprotected weight-bearing. Loss of some motion was observed in twelve patients, but the functional gain outweighed the loss of knee mobility. Seven major complications occurred in the sixteen patients, but none of them affected the outcome.

MeSH terms

  • Adolescent
  • Adult
  • Arthroplasty / methods*
  • Child
  • Follow-Up Studies
  • Hemarthrosis / etiology
  • Hemarthrosis / surgery*
  • Hemophilia A / complications*
  • Humans
  • Joint Prosthesis / methods*
  • Knee Joint / diagnostic imaging
  • Knee Joint / surgery*
  • Male
  • Preoperative Care
  • Radiography
  • Recurrence
  • Synovectomy*
  • Synovitis / complications
  • Time Factors