Genital ulcers associated with human immunodeficiency virus-related immunosuppression in female sex workers in Abidjan, Ivory Coast

J Infect Dis. 1995 Nov;172(5):1371-4. doi: 10.1093/infdis/172.5.1371.

Abstract

A cross-sectional study among female sex workers in Abidjan was conducted to study the association between sexually transmitted diseases and human immunodeficiency virus (HIV) infection and HIV-related immunosuppression. Among 1209 women tested for HIV, 962 (80%) were seropositive. HIV infection was independently associated with a longer duration of sex work, a lower price for intercourse, being an immigrant, and having a positive Treponema pallidum hemagglutination test (P < .05). Genital ulcers (25% vs. 5%), genital warts (14% vs. 4%), Neisseria gonorrhoeae (32% vs. 16%), Trichomonas vaginalis (27% vs. 17%), and syphilis (27% vs. 17%) were more frequent (P < .05) in HIV-infected than -uninfected women. Among HIV-infected women, the proportions with a genital ulcer were 17%, 25%, and 36% for those with > 28%, 14%-28%, and < 14% CD4 cells, respectively (P < .001). This study suggests that genital ulcers are an opportunistic disease in female sex workers in Abidjan.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • AIDS-Related Opportunistic Infections / epidemiology
  • AIDS-Related Opportunistic Infections / immunology*
  • Adult
  • Animals
  • Condylomata Acuminata / epidemiology
  • Condylomata Acuminata / immunology
  • Confidence Intervals
  • Cote d'Ivoire / epidemiology
  • Cross-Sectional Studies
  • Female
  • Genital Diseases, Female / epidemiology
  • Genital Diseases, Female / immunology
  • Gonorrhea / epidemiology
  • Gonorrhea / immunology
  • HIV Infections / complications
  • HIV Infections / epidemiology
  • HIV Infections / immunology*
  • HIV Seronegativity
  • HIV Seropositivity / complications
  • HIV Seropositivity / immunology*
  • Humans
  • Immune Tolerance
  • Male
  • Odds Ratio
  • Sex Work*
  • Sexual Behavior
  • Socioeconomic Factors
  • Syphilis / epidemiology
  • Syphilis / immunology
  • Time Factors
  • Trichomonas Infections / epidemiology
  • Trichomonas Infections / immunology
  • Trichomonas vaginalis