Arab population data on the PCR-based loci: HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc, and D1S80

J Forensic Sci. 1995 Sep;40(5):888-92.

Abstract

Allele and genotype frequencies for seven polymerase chain reaction (PCR)-based DNA genetic markers were determined in an Arab sample population. The loci analyzed were HLA-DQA1, LDLR, GYPA, HBGG, D7S8, Gc and D1S80. Results were obtained from the first six loci using the AmpliType HLA-DQ alpha DNA and AmpliType PM PCR Amplification and Typing Kits. The VNTR locus D1S80 PCR product was analyzed by polyacrylamide electrophoresis and silver staining. All loci meet Hardy-Weinberg expectations. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in the Arab population.

MeSH terms

  • Alleles
  • Arabs / genetics*
  • Base Sequence
  • Black People
  • Blood Stains
  • DNA / analysis*
  • Gene Amplification
  • Gene Frequency
  • Genetic Markers
  • Genetics, Population*
  • Genotype
  • Humans
  • Immunogenetics*
  • Likelihood Functions
  • Molecular Sequence Data
  • Paternity
  • Polymerase Chain Reaction
  • White People

Substances

  • Genetic Markers
  • DNA