Surgical intervention for infective endocarditis in infancy and childhood

Ann Thorac Surg. 1995 Jul;60(1):90-5.


Background: Infective endocarditis is an uncommon but serious disease in children. Optimal treatment strategy, especially surgical indications, continues to evolve.

Methods: Retrospective review of 98 patients treated for infective endocarditis during the past 13 years at the Royal Children's Hospital, including medically and surgically treated patients.

Results: Thirty of 98 patients had surgical intervention with 6.7% hospital mortality, and 76% survival probability at 45 months. The remaining patients were treated medically, with 10% hospital mortality and 52% 5-year survival probability. The incidence of structural heart disease, congestive heart failure, and spectrum of organisms was similar in the two groups.

Conclusions: Despite advances in antibiotic therapy, early surgical intervention is required in a significant subset. Concurrent intracardiac repair may be appropriate.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Endocarditis, Bacterial / drug therapy
  • Endocarditis, Bacterial / microbiology
  • Endocarditis, Bacterial / mortality
  • Endocarditis, Bacterial / surgery*
  • Humans
  • Infant
  • Infant, Newborn
  • Retrospective Studies
  • Staphylococcal Infections / surgery
  • Survival Rate