Mitochondria: beyond oxidative phosphorylation

Biochim Biophys Acta. 1995 May 24;1271(1):123-6. doi: 10.1016/0925-4439(95)00018-y.

Abstract

Mitochondria are essential eukaryotic organelles that perform many functions in addition to oxidative phosphorylation. Some of these functions are still poorly understood or as yet undiscovered, but may resemble already known functions in bacteria. The rapidly growing sequence information on bacterial genes, the polymerase chain reaction, and gene disruption in yeast thus offer a powerful approach for discovering new mitochondrial functions.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • ATP-Dependent Proteases
  • Adenosine Triphosphatases / chemistry
  • Adenosine Triphosphatases / metabolism
  • Amino Acid Sequence
  • Animals
  • Bacteria / metabolism*
  • DNA, Mitochondrial / metabolism
  • Genes, Bacterial
  • Heat-Shock Proteins / chemistry
  • Heat-Shock Proteins / metabolism
  • Mitochondria / metabolism*
  • Models, Biological
  • Molecular Sequence Data
  • Oxidative Phosphorylation
  • Protein Biosynthesis
  • Protein Precursors / metabolism*
  • Protein Processing, Post-Translational*
  • Saccharomyces cerevisiae / genetics
  • Saccharomyces cerevisiae / metabolism
  • Serine Endopeptidases / chemistry
  • Serine Endopeptidases / metabolism

Substances

  • DNA, Mitochondrial
  • Heat-Shock Proteins
  • Protein Precursors
  • ATP-Dependent Proteases
  • Serine Endopeptidases
  • Adenosine Triphosphatases