The role of tranexamic acid in the treatment of giant hemangiomas in newborns

Am J Pediatr Hematol Oncol. 1993 Nov;15(4):383-5.


Giant hemangiomas occurring in the neonatal period often present a therapeutic challenge, especially when confounded by consumptive coagulopathy (Kasabach-Merritt syndrome). We treated three infants with tranexamic acid after therapy with corticosteroids was ineffective. One patient had a partial response. The remaining two developed progressive disease.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Hemangioma / drug therapy*
  • Hemangioma, Cavernous / drug therapy*
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Prednisone / therapeutic use
  • Tranexamic Acid / therapeutic use*


  • Tranexamic Acid
  • Prednisone