Calcium channel blocker overdose

Am J Emerg Med. 1995 Jul;13(4):444-50. doi: 10.1016/0735-6757(95)90137-X.


A case of diltiazem overdose with significant hemodynamic compromise is presented. Multiple therapeutic modalities were attempted with limited results. Control was finally achieved with a combination of norepinephrine, dobutamine, and cardiac pacing. Invasive pulmonary monitoring parameters are reported and were important in the management of this patient. The management of calcium channel blocker overdose and the various available therapeutic modalities are discussed.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Calcium Channel Blockers / pharmacokinetics
  • Calcium Channel Blockers / pharmacology
  • Calcium Channel Blockers / poisoning
  • Cardiac Pacing, Artificial
  • Combined Modality Therapy
  • Diltiazem / poisoning*
  • Dobutamine / administration & dosage
  • Drug Overdose
  • Female
  • Humans
  • Norepinephrine / administration & dosage
  • Poisoning / therapy
  • Suicide, Attempted


  • Calcium Channel Blockers
  • Dobutamine
  • Diltiazem
  • Norepinephrine