Review
doi: 10.1016/s0968-0004(00)89007-6.
ICE-like proteases in apoptosis
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- PMID: 7610484
- DOI: 10.1016/s0968-0004(00)89007-6
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Review
ICE-like proteases in apoptosis
Trends Biochem Sci.
1995 May.
Abstract
The discovery of structural and functional similarities between the product of the nematode cell-death gene ced-3 and mammalian interleukin-1 beta-converting enzyme (ICE) is providing important insights into the molecular mechanism of apoptosis. This article summarizes the current knowledge of ICE and its homologues, and how these may be involved in regulating apoptosis.
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