Purpose/methods: The effect of exercise on the iris contour was investigated with ultrasound biomicroscopy in two patients with pigmentary glaucoma.
Results/conclusion: Ten minutes of bicycle exercise strikingly increased the iris concavity. After Nd:YAG laser iridotomy the iris remained plane after a repeated exercise test. We believe that exercise increased the ocular pulse, which augmented cyclic aqueous movements through the pupil. Combined with a reverse pupillary block, the resulting intermittent excessive iris concavity caused pigment dispersion.