[Noninvasive ventilation after lung transplantation]

Med Klin (Munich). 1995 Apr;90(1 Suppl 1):26-8.
[Article in German]


Background: Non-invasive mechanical ventilation (NIPPV) is an accepted choice of treatment in patients with chronic pulmonary disease and/or acute respiratory failure. Recently NIPPV was also proposed in the postoperative weaning period.

Patients and methods: Six of 30 patients after lung transplantation were were extubated despite a weaning failure was predicted using well accepted weaning criteria. Therefore, the 6 patients were treated with intermittent-noninvasive ventilation using assisted modes of mechanical ventilation (PSV/CPAP).

Results: Both, oxygenation (increase in paO2: 18 mm Hg during PSV, 11 mm Hg during CPAP) and pulmonary mechanics (decrease in respiratory rate: 14/min during PSV, 10/min during CPAP; increase in tidal volume: 5 ml/kg during PSV, 3 ml/kg KG during CPAP) improved and the energy expenditure decreased (19% during PSV, 12% during CPAP).

Conclusion: Non-invasive ventilation after lung transplantation enables earlier extubation and prevents weaning failure.

Publication types

  • English Abstract

MeSH terms

  • Humans
  • Intermittent Positive-Pressure Ventilation*
  • Lung Diseases, Obstructive / physiopathology
  • Lung Diseases, Obstructive / surgery*
  • Lung Transplantation / physiology*
  • Masks
  • Oxygen / blood
  • Postoperative Care
  • Postoperative Complications / physiopathology
  • Postoperative Complications / therapy*
  • Respiratory Insufficiency / physiopathology
  • Respiratory Insufficiency / surgery*
  • Ventilator Weaning*


  • Oxygen