[Associations between arterial hypertension and other cardiovascular risk factors in subjects over 65 years of age]

Recenti Prog Med. 1995 Apr;86(4):147-54.
[Article in Italian]

Abstract

The goal of this study was to evaluate whether in subjects aged 65 or over hypertensive patients have a greater prevalence of risk factors than normotensives. 1369 subjects, aged 65 or over, have been retrospectively investigated. The following risk factors were considered: cigarette smoking, left ventricular hypertrophy, diabetes mellitus and atrial fibrillation (analyzed as dichotomous variables), B.M.I., blood concentration of total, -LDL-HDL cholesterol, triglycerides and total/HDL cholesterol ratio (analyzed as continuous variables). The mean number of risk factors was calculated in hypertensive and normotensive subjects; the association between hypertension and risk factors was evaluated using univariate and multiple logistic regression analysis. 451 subjects (32.9%) were found to be hypertensives. The average number of risk factors was significantly greater in hypertensive than in normotensive subjects (1.85 +/- 1.27 vs 1.39 +/- 1.15, p < 0.001), and, in both groups, in men than in women. Left ventricular hypertrophy (p < 0.001), total cholesterol (p < 0.001), diabetes mellitus (p < 0.001) and atrial fibrillation (p < 0.01) were found to be independently associated with the presence of hypertension. We concluded that among the elderly there is a greater prevalence of risk factors in hypertensive than in normotensive subjects and that some risk factors--left ventricular hypertrophy, atrial fibrillation, diabetes mellitus, and blood levels of atherogenic lipids--are independently associated with the presence of hypertension.

Publication types

  • Comparative Study
  • English Abstract

MeSH terms

  • Aged*
  • Aged, 80 and over
  • Analysis of Variance
  • Atrial Fibrillation / complications
  • Cardiovascular Diseases / etiology*
  • Cholesterol / blood
  • Diabetes Complications
  • Female
  • Humans
  • Hypertension / complications*
  • Hypertrophy, Left Ventricular / complications
  • Logistic Models
  • Male
  • Retrospective Studies
  • Risk Factors
  • Smoking / adverse effects
  • Triglycerides / blood

Substances

  • Triglycerides
  • Cholesterol