Multimodal therapy in life-threatening cerebral lupus erythematosus: the benefit of cerebrospinal fluid pheresis

Int Arch Allergy Immunol. 1995 Aug;107(4):592-4. doi: 10.1159/000237105.


A 27-year-old female patient with severe cerebral systemic lupus erythematosus did not respond to conventional therapy, including high-dose corticosteroids and high-dose pulsed cyclophosphamide therapy. Cerebrospinal fluid filtration (pheresis) led to rapid and lasting neurological improvement and clinical cure.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / therapy*
  • Cerebrospinal Fluid / chemistry*
  • Female
  • Filtration
  • Humans
  • Lupus Erythematosus, Systemic / therapy*