Abstract
A two-year-old, spayed female, miniature schnauzer was evaluated for respiratory distress associated with a compressive cervical mass. Generalized mycobacterial infection was diagnosed from aspirates of several enlarged lymph nodes. Tissue specimens further identified Mycobacterium avium--intracellulare using polymerase chain reaction followed by nucleic acid hybridization. Treatment with enrofloxacin, clofazamine, rifampin, and interferon did not result in long-term success.
MeSH terms
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Animals
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Anti-Infective Agents*
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Clofazimine / therapeutic use
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DNA, Bacterial / analysis
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Dog Diseases / diagnosis*
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Dog Diseases / drug therapy
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Dog Diseases / microbiology
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Dogs
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Enrofloxacin
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Female
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Fluoroquinolones*
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Interferon-alpha / therapeutic use
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Lymph Nodes / microbiology
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Lymph Nodes / pathology
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Mandible
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Mesentery
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Mycobacterium avium / drug effects
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Mycobacterium avium / genetics
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Mycobacterium avium / isolation & purification*
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Nucleic Acid Hybridization
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Polymerase Chain Reaction / veterinary
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Quinolones / therapeutic use
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Rifampin / therapeutic use
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Tuberculosis / diagnosis
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Tuberculosis / drug therapy
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Tuberculosis / microbiology
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Tuberculosis / veterinary*
Substances
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Anti-Infective Agents
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DNA, Bacterial
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Fluoroquinolones
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Interferon-alpha
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Quinolones
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Enrofloxacin
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Clofazimine
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Rifampin