Quercetin not only inhibits P-glycoprotein efflux activity but also inhibits CYP3A isozymes

Cancer Chemother Pharmacol. 1995;36(5):448-50. doi: 10.1007/BF00686195.
No abstract available

Publication types

  • Letter
  • Comment

MeSH terms

  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / drug effects*
  • ATP Binding Cassette Transporter, Subfamily B, Member 1 / metabolism
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / enzymology
  • Cytochrome P-450 CYP2E1
  • Cytochrome P-450 Enzyme Inhibitors*
  • Humans
  • Isoenzymes / antagonists & inhibitors
  • Mixed Function Oxygenases / antagonists & inhibitors*
  • Quercetin / pharmacology*
  • Tumor Cells, Cultured

Substances

  • ATP Binding Cassette Transporter, Subfamily B, Member 1
  • Cytochrome P-450 Enzyme Inhibitors
  • Isoenzymes
  • Quercetin
  • Mixed Function Oxygenases
  • Cytochrome P-450 CYP2E1