[Biological properties of interleukin 10]

Postepy Hig Med Dosw. 1994;48(4):363-70.
[Article in Polish]

Abstract

Interleukin-10 (IL-10) is produced predominantly by T-helper lymphocytes and macrophages. IL-10 inhibits lymphocyte-induced cytokine production (CSIF--cytokine synthesis inhibitory factor), cooperates in B lymphocytes activation as well as macrophages--monocytes deactivation (MDF--macrophage deactivating factor). Due to its immunosuppressive properties IL-10 may be used in therapy of some T-cell induced diseases.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / immunology
  • Acquired Immunodeficiency Syndrome / therapy
  • Humans
  • Interleukin-10 / biosynthesis
  • Interleukin-10 / immunology*
  • Interleukin-10 / therapeutic use
  • Lymphocytes / immunology
  • Macrophages / immunology
  • Mast Cells / immunology

Substances

  • Interleukin-10