Screening for Barrett's esophagus by balloon cytology

Am J Gastroenterol. 1995 Aug;90(8):1230-2.


Objective: to determine whether balloon cytology would allow a nonendoscopic diagnosis of Barrett's esophagus.

Methods: In 10 unselected patients with Barrett's esophagus, balloon cytology was performed with a Brandt esophageal cytology balloon catheter prior to endoscopy/esophageal biopsy. Specimens were cytologically evaluated for the presence of goblet cells and/or dysplasia.

Results: No patient had goblet cells or definitive columnar cell dysplasia.

Conclusion: This technique with a commercially available balloon catheter does not allow for a nonendoscopic diagnosis of Barrett's esophagus.

MeSH terms

  • Barrett Esophagus / diagnosis
  • Barrett Esophagus / pathology
  • Barrett Esophagus / prevention & control*
  • Biopsy
  • Catheterization*
  • Cytodiagnosis / methods
  • Esophagoscopy
  • Esophagus / pathology*
  • Female
  • Humans
  • Male
  • Mass Screening / methods*
  • Middle Aged
  • Pilot Projects
  • Specimen Handling