The effect of a Plantago ovata seed containing preparation on appetite variables, nutrient and energy intake

Int J Obes Relat Metab Disord. 1995 May;19(5):338-42.


Objectives: Investigation of a Plantago ovata seed containing supplement (Plantaginis ovatae semen and testa) to determine its effect on appetite variables, nutrient and energy intake in normal subjects.

Design: Triple blind (subjects, investigators and statisticians) cross-over design. Three, 3-day study periods when subjects were given the following treatments in randomised order: Plantago ovata preparation (20 g granules with 200 ml water), placebo (20 g granules with 200 ml water), or water (200 ml) 3 hs pre-meal and the same dose immediately pre-meal. A set meal was given at lunch time after the supplement to subjects who had fasted overnight.

Setting: Metabolic unit of King's College London.

Subjects: Seventeen female subjects, all classified as non-restrained eaters.

Main outcome measures: Visual analogue scales were completely premeal, postmeal and at hourly intervals for 3 hs after the meal. All food consumed on the meal day, and the following day was weighed.

Results: There was a significant difference in fullness at 1 h post-meal between Plantago and placebo, and also Plantago and water. Total fat intake was significantly lower in g/d and as a percentage of energy on the day of the meal after Plantago compared with water.

Conclusions: This plantago ovata containing product, which is already taken by many people world-wide to control bowel function, may be a useful supplement in weight control diets as it affects fat intake, and may have some effect on the subjective feeling of fullness.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Appetite / drug effects*
  • Appetite / physiology
  • Cross-Over Studies
  • Dietary Fiber* / administration & dosage
  • Eating / drug effects*
  • Eating / physiology
  • Energy Intake / drug effects
  • Energy Intake / physiology
  • Female
  • Food, Fortified
  • Humans
  • Hunger / drug effects
  • Hunger / physiology
  • Nutritional Physiological Phenomena
  • Plantago
  • Plants, Medicinal
  • Psyllium / pharmacology*
  • Satiation / drug effects
  • Satiation / physiology
  • Seeds
  • Surveys and Questionnaires


  • Dietary Fiber
  • Psyllium